Company description:

OXB is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, OXB has more than 30 years of experience in viral vectors, the driving force behind the majority of gene therapies.

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patients cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).

OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.

Job description:

Join Us in Changing Lives

At?OXB, our people are at the heart of everything we do.Wereon a mission to enable life-changing therapies to reach patients around the worldandwerelooking for passionate individuals who embody our core values every day:?Responsible, Responsive, Resilient, and Respectful.

Were currently recruiting for a?Director, Global MSAT to join our Global MSAT team. Based in the UK ideally close by our Oxford location, you be lead the implementation and maintenance of OXBs platforms across the global network. The role will focus in areas of process and material harmonization, new technology introduction, continuous process improvement, and cross site process transfers. You will work closely with the site functional teams, playing a key part in advancing our mission and making a real difference.

Your responsibilities in this role would be:

• Develop and oversee rollout and implementation of harmonization projects into the Global network sites, developing deployment plans cross functionally and supporting the on-site teams during all phases of transfer to meet business targets
• Lead on assigned global project implementation initiatives to sites and ensure all project timelines and objectives are consistently monitored and delivered
• Strengthen, standardise and drive consistency in execution across OXBs global network, with tactical focus on the companys varied complex activities and multi-vector strategy
• Develop and define OXBs strategies for transfer of new platforms & processes and new technologies and lead implementation with the site teams
• Oversee technology transfers for early stage/late stage/commercial projects, including PPQ campaign support
• Provide technical leadership and know-how directly with cross functional teams across the OXB operations network and strengthen cross-site support and SME knowledge sharing
• Identify improvement projects to enhance capabilities and resolve current and future challenges on Upstream, Downstream & Fill Finish processes, integrated continuous processes, equipment selection and implementation, single use technologies and process automation
• Responsible for ensuring manufacturing process network alignment through platform strategy documents and business process

Profile description:

We are looking for:

• Degree in Science / Engineering or related technical discipline, or equivalent level of work experience
• Extensive knowledge and practical experience of technical areas relevant to viral vector CDMO technologies, and processes
• Proven proficiency in supporting regulatory submissions
• Significant industrial experience in scale-up and industrialisation of GMP manufacturing bioprocesses, technical support & process troubleshooting
• Recognised SME in a technical field of expertise covering areas such as technology transfer, upstream & downstream processes, aseptic fill finish, analytics, optimisation and scale up, single use disposable systems, process validation and GMP manufacturing operations
• Strong expertise in understanding, utilizing, and integrating various unit operations with the ability to assess and recommend the best tools and technologies for business needs
• Experienced project manager, with skills in developing staff and/or processes and managing resources,
• Excellent communication skills with the ability to work effectively and influence in diverse and interdisciplinary teams both internally and externally with customers.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the worlds most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXBs world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us?

• ??Competitive total reward packages
• ??Wellbeing programsthat support your mental and physical health
• ??Career development opportunitiesto help you grow and thrive
• ??Supportive, inclusive, and collaborative culture
• ??State-of-the-art labs and manufacturing facilities
• ?? A company that lives its values:Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, were future-focused and growing fast. We succeed togetherthrough passion, commitment, and teamwork.

Ready to Make a Difference?

We offer:

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patients cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. xbpsjku These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.